41. Typical changes in the airways include an increase in eosinophils and thickening of the lamina reticularis. 42. Major basic protein, eosinophil peroxidase, and eosinophil cationic protein are toxic to many tissues. 43. Major basic protein, eosinophil peroxidase, and eosinophil cationic protein are toxic to many tissues. 44. CCR5 is predominantly expressed on T cells, macrophages, dendritic cells, eosinophils and microglia. 45. The common characteristic among different causes of EP is eosinophil overreaction or dysfunction in the lung. 46. A minimum of 15 eosinophils per high-power field are required to make the diagnosis. 47. It is also secreted by eosinophils . 48. Eosinophil granulocytes appear in large numbers in inflammation sites and in response to certain parasitic infections.49. ECP concentrations in plasma and other body fluids increase during inflammatory reactions marked by activated eosinophils . 50. EMR1 expression in human is restricted to eosinophils and is a specific marker for these cells.