41. Relative to estradiol benzoate, estradiol dipropionate has enhanced and very prolonged effects. 42. Relative to estradiol benzoate, estradiol dipropionate has enhanced and very prolonged effects. 43. However, the manipulation of estradiol does not increase or decrease paternal behaviors. 44. It is an estrogen ester, specifically, and an ester of estradiol . 45. In contrast to estradiol and testosterone, progesterone proved more difficult to esterify. 46. Estradiol is also used as other prodrugs like estradiol valerate and estradiol acetate.47. Estradiol is also used as other prodrugs like estradiol valerate and estradiol acetate. 48. Estradiol is also used as other prodrugs like estradiol valerate and estradiol acetate. 49. Steady-state levels of estradiol are achieved after three days of applications. 50. Transdermal estradiol bypasses the intestines and liver and hence first-pass metabolism.
