41. Iron is released from ferritin for use by ferritin degradation, which is performed mainly by lysosomes. 42. Iron is released from ferritin for use by ferritin degradation, which is performed mainly by lysosomes. 43. Ferritin is also used as a marker for iron overload disorders, such as hemochromatosis or hemosiderosis.44. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. 45. Excess iron, ferritin , and red blood cells may result in xanthochromia of the cerebrospinal fluid. 46. The concentration of ferritin has been shown to increase in response to stresses such as acute phase protein. 47. A normal C-reactive protein can be used to exclude elevated ferritin caused by acute phase reactions. 48. Furthermore, ferritin has significant non storage roles within the body, such as protection from oxidative damage. 49. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. 50. The most useful is a ferritin test, which can be done as part of a routine blood test.
