This deletion, corresponding to exon 5 of the mouse hydroxylase gene, causes a frameshift mutation and premature termination of the polypeptide chain in human.
42.
Some of these are full-length, intact genes; others are pseudogenes ) typically with frameshift mutations, premature stop codons, or fragmentation.
43.
The frameshift mutation will also alter the first stop codon ( " UAA ", " UGA " or " UAG " ) encountered in the sequence.
44.
When a frameshift mutation is observed it is compared against the Human Genome Mutation Database ( HGMD ) to determine if the mutation has a damaging effect.
45.
This is distinct from a frameshift mutation, as the nucleotide sequence ( DNA or RNA ) is not altered only the frame in which it is read.
46.
When analyzing the baiji genome, scientists have found that there are four genes that have lost their function due to a frameshift mutation or premature stop codons.
47.
Would it be consitered a nonsense mutation, Frameshift mutation or a missense mutation ? Preceding talk ) 16 : 25, 21 February 2011 ( UTC)
48.
The first was to prove that all overlapping genetic Crick, Brenner, Barnett, Watts-Tobin et al . experiment of 1961, which discovered frameshift mutations.
49.
Of the seven reported frameshift mutations occurring in poly C-tracts in RAI1, four cases ( ~ 57 % ) occur at this heptameric C-tract.
50.
In 2005, an American family was found to also possess a frameshift mutation in the DISC1 gene, which again co-segregated with schizophrenia and schizoaffective disorder.
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