A gene in a somatic cell of an individual may forego replication to promote the transmission of its copies in the germ line cells.
42.
Such germ line mutations are shown in a box at the left of the figure, with an indication of their contribution to DNA repair deficiency.
43.
These germ line mutations are indicated in a box at the left of the figure with an arrow indicating their contribution to DNA repair deficiency.
44.
This led the way to treatments for other genetic diseases and increased interest in germ line gene therapy-therapy affecting the gametes and descendants of patients.
45.
All we know at this point is that the germ line stem cells must be the starting point for the events that control life span.
46.
It was the first known experiment in which the human inheritable gene pattern, called the germ line, was altered in a full-term baby, he said.
47.
"We can't completely rule it out yet, but we think the number of bacteria genes that transferred to the human germ line is zero ."
48.
Following the Chernobyl disaster, it was found that the germ line of irradiated fathers suffered minisatellite mutations in the DNA, which was inherited by descendants.
49.
Some germ line mutations in DNA repair genes cause up to 100 % lifetime chance of cancer ( e . g ., p53 mutations ).
50.
But she opposes the use of altered embryonic stem cells to make changes to an individual's germ line, as is done routinely in making knock-out mice.
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