41. The cytosolic HSR is mainly mediated by the transcription factor family HSF ( heat shock family ). 42. AHSA1 has been shown to interact with Heat shock protein 90kDa alpha ( cytosolic ), member A1. 43. Under heat shock , IbpB protein dissociates to give two smaller subunits and also rearranges its tertiary structure. 44. HSPB6 also known as hsp20 is a 17-kDa member of the small heat shock family of proteins. 45. Several heat shock elements ( HSE ) are located upstream of Hsp90A allowing for its inducible expression. 46. Heat shock proteins are generally responsible for preventing damage to proteins in response to high levels of heat.47. The hormone receptor without ligand binding interacts with heat shock proteins and prevents the transcription of targeted genes. 48. The distal HSE is required for heat shock induction and the proximal HSE functions as a permissive enhancer. 49. They produce heat shock proteins, but unlike other animals they do this not in direct response to heat. 50. The induction of sex by heat shock is mediated by oxidative stress that likely also causes oxidative DNA damage.
