41. Further analyses of fibrolamellar hepatocellular carcinoma tissues show an increase in protein levels of this DNAJ-PKAc fusion protein. 42. Worldwide hepatitis C is the cause of 27 % of cirrhosis cases and 25 % of hepatocellular carcinoma . 43. FHCC often does not produce alpha fetoprotein ( AFP ), a widely used marker for conventional hepatocellular carcinoma . 44. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. 45. UHRF1 has recently been identified as a novel oncogene in hepatocellular carcinoma , the primary type of liver cancer. 46. Thymidylate synthase is induced by a transcription factor LSF / TFCP2 and LSF is an oncogene in hepatocellular carcinoma . 47. SNPs on GALNT14 have been shown to be associated to the chemotherapy responses of patients with advanced hepatocellular carcinoma . 48. The usual outcome is poor, because only 10 20 % of hepatocellular carcinomas can be removed completely using surgery. 49. It has orphan drug designation from US FDA and EUMA for the treatment of hepatocellular carcinoma ( HCC ). 50. Transgenic mice expressing the X protein in liver are more likely than the wild type to develop hepatocellular carcinoma .
