41. With reversal of immunosuppression , there is paradoxical increased inflammation as the recovering immune system recognises the fungus. 42. Low-attenuated vaccine strains may cause damage to the bursa of Fabricius and immunosuppression in susceptible chicks. 43. Managing people with HIV, hepatitis and posttransplant immunosuppression -related problems is a very complex medical management problem, 44. IFN therapy causes immunosuppression , in particular through neutropenia and can result in some infections manifesting in unusual ways. 45. The only consensus was on treating patients with advanced immunosuppression ( CD4 counts less than 350 / ?L ). 46. Underlying immunosuppression may be medically manageable once it is identified, and this helps prevent recurrence of candidal infections. 47. Long-term immunosuppression increases the risk of developing life-threatening infections, kidney damage, and cancer. 48. Leflunomide, a pyrimidine synthesis inhibitor is now generally accepted as the second treatment option behind reduction of immunosuppression . 49. She is regarded as a world leader in nerve regeneration enhancement and in developing minimal immunosuppression regimens following transplantation. 50. Long-term immunosuppression treatment leaves an individual more vulnerable to infection, diabetes, weakened bones and other problems.