A 2013 in vitro study using shorter blue band spectrum LED lights indicated that prolonged exposure may permanently damage the pigment epithelial cells of the retina.
42.
"In vivo " as well as in vitro studies discovered that inhibition of INa and IKr by AZD1305 is much greater in atrial versus ventricular myocytes.
43.
In vitro studies showed that tamoxifen acts as an estrogen agonist on bone and inhibits the resorbing activity of osteoclasts ( disruption of bone tissue ).
44.
In vitro studies with recombinant proteins indicate that the CBR1 V88 isoform has a higher Vmax towards the substrates menadione ( vitamin K 3 ) and daunorubicin.
45.
A scientific review in 2013 came to the conclusion that epidemiological and in vitro studies generally converge sufficiently to conclude that phthalate anti-androgenicity is plausible in adult men.
46.
_In vitro studies, which involve cells or small samples of tissue that have been removed from humans or animals and then exposed to pollutants to determine what damage may occur.
47.
Despite the overwhelming evidence for the phosphorylation regulation of calponin obtained from in vitro studies, phosphorylated calponin is not readily detectable in vivo or in living cells under physiological conditions.
48.
Intensive research has so far not confirmed this hypothesis, partly because lithium can also act on a number of other enzymes in this pathway, complicating results from in vitro studies.
49.
Though no specific defect has been formally associated with mutations in Cripto, in vitro studies that disrupt gene function at various times during development have provided glimpses of possible malformations.
50.
However, in vitro studies with other divalent metal ions have shown that zinc and manganese are preferred over magnesium, while copper and nickel are not accepted by the enzyme at all.
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