A reviewer at the Food and Drug Administration decided to question GlaxoSmithKline about a finding that teenagers and children given the company's drug, Paxil, were more likely to suffer " emotional lability " than those given placebos.
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Nervous breakdowns may share some features of acute stress disorder and post-traumatic stress disorder, in that these each occur in response to an external stressor, and may be marked with sleep disturbance, diminished concentration, and mood lability.
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According to the DSM-V, a diagnosis of PMDD requires the presence of at least five of these symptoms with one of the symptoms being number 1-4 ( marked lability, irritability, depressed mood, anxiety and tension ).
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Due to the chemical lability of PRA, which has a half-life of 38 seconds at PH 7.5 and 37 �C, researchers have suggested that the compound is channeled from amidophosphoribosyltransferase to GAR synthetase " in vivo ."
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Due to the chemical lability of PRA, which has a half-life of 38 seconds at PH 7.5 and 37 �C, researchers have suggested that the compound is channeled from Amidophosphoribosyltransferase to GAR synthetase " in vivo ".
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Emotional lability is seen or reported in various conditions including borderline personality disorder, histrionic personality disorder, hypomanic or manic episodes of bipolar disorder, and neurological disorders or brain injury ( where it is termed pseudobulbar affect ), such as after a stroke.
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The most debilitating symptoms are emotional and include " irritability, depression, mood lability, anxiety, feelings of loss of control, difficulty concentrating and fatigue . " The physical symptoms include " abdominal bloating, breast tenderness, headache and generalized aches ."
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After the irregularly high levels of adrenaline consumed during sympathetic nervous system activation, an individual may display signs and symptoms of post-traumatic stress disorder, and it is common for the person to display extreme emotional lability and fatigue, regardless of their actual physical exertion.
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The reaction of NfF with alcohols highlights the lability of alkyl nonaflates in most cases, the final product of the reaction is either an alkyl fluoride ( from F " attack on the intermediate alkyl nonaflate ) or an olefin ( from elimination of NfOH from the intermediate nonaflate ).
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As a general example, if a molecule exists in a particular conformation for a short lifetime, before adopting a lower energy conformation ( structural arrangement ), the former molecular structure is said to have'high lability'( such as C 25, a 25-carbon fullerene spheroid ).
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