The drug is in the form of an inactive lactone that is hydrolyzed after ingestion to produce the active agent.
42.
It is created by substituting a ketogroup for the cladinose sugar and adding a carbamate ring in the lactone ring.
43.
Reaction with chloral hydrate in the presence of potassium bisulfate yields the lactone of tetra-oxydiphenyl methane carboxylic acid.
44.
This causes the expression of RhlR which then binds its autoinducer, N-( butryl )-homoserine lactone.
45.
The metal ions assist in polarizing the lactone bond, increasing the electrophilicity of the lactone ring s carbonyl carbon.
46.
The metal ions assist in polarizing the lactone bond, increasing the electrophilicity of the lactone ring s carbonyl carbon.
47.
Artemisinin contains an undesirable lactone group and which is replaced by an acetal through organic reduction with potassium borohydride and methoxylation:
48.
Transformation between leuco and colored form of crystal violet lactone in response to varying acidity, which is caused by changing temperature
49.
Treatment of an ester or lactone with AlMe 3 or AlMe 2 Cl affords the corresponding Weinreb amide in good yields.
50.
Withaferin A, a sterodial lactone from " Withania Somnifera " plant is known to inhibit Sp1 transcription factor.
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