41. Stimulation of pDCs leads to an increase of macrophages present in plaques. 42. The brown pigment is lipofuscin in macrophages , not melanin. 43. IL-23 is produced by dendritic cells and macrophages . 44. Intestinal macrophage dysregulation has been implicated in inflammatory bowel disease. 45. These cells include dendritic cells, monocytes, and macrophages . 46. Those infecting the macrophages or endothelial cells develop into megaloschizonts. 47. Clodronic acid is also used in experimental medicine to selectively deplete macrophages . 48. Activated macrophages and monocytes secrete HMGB1 as a cytokine mediator of Inflammation. 49. Lack of RIP140 leads to an inhibition of proinflammatory pathways in macrophages . 50. Tumor cells can also evade macrophage phagocytosis through the expression of CD47.
