41. In zebrafish, Squint and Cyclops are responsible for animal-vegetal mesoderm formation. 42. Gsc is found in high concentrations in the dorsal mesoderm and endoderm during gastrulation. 43. An endoskeleton derived from the mesoderm is present in echinoderms, sponges and some cephalopods. 44. The mammalian kidney develops from intermediate mesoderm . 45. This is distinct from vasculogenesis, which is the endothelial cells from mesoderm cell precursors. 46. The new mesoderm then splits, creating the pocket-like cavity of the coelom. 47. Tissues derived from the head mesoderm include connective tissue and the muscles of the face. 48. BMP4 antagonizes organizer tissue and is expressed in early development in ectoderm and mesoderm tissue. 49. Her claim went counter to the belief that only mesoderm could form bones and cartilage. 50. It may be involved in mesoderm segmentation.