In addition, whereas 9?-fluoro-11?-hydroxyprogesterone has pronounced mineralocorticoid effects, BKP lacks such effects.
42.
Mineralocorticoids ( such as aldosterone ) produced in the zona glomerulosa help in the regulation of blood pressure and stress situations.
43.
Fludrocortisone is the only pharmaceutically available mineralocorticoid and is usually used in doses of 0.05 to 2 mg daily.
44.
One particularly serious problem, the fainting and thus injury from falling ) often responds to fludrocortisone, a synthetic mineralocorticoid.
45.
EEF1A1 is downregulated in myocardial infarction and potentially participates in cardiovascular disease through its interactions with mineralocorticoid receptors in the heart.
46.
This layer is the main site for production of aldosterone, a mineralocorticoid, by the action of the enzyme aldosterone synthase.
47.
Although widely used, evidence on their efficacy and safety is limited, with the exception of mineralocorticoid antagonists such as spironolactone.
48.
Mineralocorticoid effects can include salt and water retention, extracellular fluid volume expansion, hypertension, potassium depletion, and metabolic alkalosis.
49.
Low levels ( < 7 ) during hyperkalemia may indicate mineralocorticoid deficiency, especially if accompanied by hyponatremia and high urine Na.
50.
Progesterone in turn is the precursor of the mineralocorticoid aldosterone, and after conversion to 17?-hydroxyprogesterone, of cortisol and androstenedione.
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