41. They have a high molecular weight and exist as either membrane-bound or secretory mucins . 42. Abnormal deposits of mucin are responsible for the non-pitting facial edema seen in untreated hypothyroidism. 43. Mucins are constituents of one class of glycoproteins : sialic acid-containing glycoproteins, or mucoproteins.44. Mucins are secreted as massive aggregates of proteins with molecular masses of roughly 1 to 10 million Da.45. The remainder of the cell's cytoplasm is occupied by membrane-bound secretory granules containing mucin . 46. This negatively charged residue is found in complex glycans on mucins and glycoproteins found at the cell membrane. 47. A study of SRCC colorectal cancers compared mucin -rich SRCC tumors and mucin-poor SRCC tumors. 48. A study of SRCC colorectal cancers compared mucin-rich SRCC tumors and mucin -poor SRCC tumors. 49. These are shorter than their surface counterpart and contain lesser quantities of mucin granules in their apical surface. 50. Five colon-related domains had genes for apoptosis, cell proliferation, ion transporter and mucin production.