41. Botulinum toxin causes temporary muscular paralysis by inhibiting acetylcholine release at the neuromuscular junction. 42. Basmajian demonstrated practical applications for neuromuscular rehabilitation, pain management, and headache treatment. 43. Another potentially disturbing complication where neuromuscular blockade is employed is'anesthesia awareness '. 44. Neuromuscular junction diseases can be of autoimmune origin.45. It can be neuromuscular disease or autosomal recessive. 46. Some conditions, such as myositis, can be considered both neuromuscular and musculoskeletal. 47. Acetylcholine concentrations then increase at neuromuscular junctions to cause involuntary contraction of all muscles. 48. In this sense, tubocurarine is the prototypical adjunctive neuromuscular non-depolarizing agent. 49. Sugammadex is a newer drug for reversing neuromuscular block by rocuronium in general anaesthesia. 50. In neuromuscular disease evaluation, it is important to perform musculoskeletal and neurologic examinations.
