41. Despite such problems, researchers are hopeful about the newest neurotrophic factor, glial cell-derived neurotrophic factor. 42. It's a modified form of a naturally occurring protein known as CNTF ( ciliary neurotrophic factor ). 43. The regeneration effects of oncomodulin outcompetes other neurotrophic factors like BDNF, CNTF, and GDNF ( 4 ). 44. As such, TrkC mediates the multiple effects of this neurotrophic factor, which includes neuronal differentiation and survival. 45. In one experiment, Dr . Kennedy adapted the neurotrophic electrode to read local field potentials ( LFPs ). 46. Brain-derived neurotrophic factor is among the chemotactic factors that stimulate Numb-mediated chemotaxis during cell migration. 47. Localized delivery of soluble neurotrophic factors may help promote the rate of axon regeneration observed within these graft conduits. 48. It may be that each type of neuron needs a special mix of neurotrophic factors to survive, he said. 49. The substance, brain-derived neurotrophic factor, has long been known to help brain cells mature and survive. 50. He then showed that neurotrophic factors can modify the effects of neurotransmitters on neurite outgrowth, synaptogenesis and cell survival.
