41. A perturbation of oligodendrocyte maturation and myelination therefore might be an underlying reason for the neurological deficits. 42. Snyder said the results suggested that the brains somehow signaled to the stem cells that oligodendrocytes were needed. 43. Molecular mediators are released by neurons, microglia, oligodendrocyte lineage cells, synaptic function and neural plasticity. 44. It is thought to inhibit not only axon regeneration but also regulate oligodendrocyte maturation by inhibiting OPC differentiation. 45. Oligodendrocytes are glial cells that produce a fatty substance called myelin, which wraps around axons in layers.46. Because the gene is disrupted, the oligodendrocytes , the special cells that do the cladding, are ineffective. 47. The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte . 48. The experiment determined that factors from the younger mice reversed CNS demyelination in older mice by revitalizing the oligodendrocytes . 49. Myelin is made by Schwann cells in the peripheral nerves and by cells called oligodendrocytes in the central nervous system. 50. The myelin sheaths of Oligodendrocytes do not have neurolemma because excess cytoplasm is directed centrally toward the Oligodendrocyte cell body.
