He was one of the inventors and developers of the life-saving method called oral rehydration therapy for adults and children suffering fluid loss from cholera and other infectious diarrheal illnesses.
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In more severe cases, correction of a dehydrated state is accomplished by the replenishment of necessary water and electrolytes ( through oral rehydration therapy or fluid replacement by intravenous therapy ).
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Dr . Dilip Mahalanabis made his major contribution to oral rehydration therapy in 1971 while working in Calcutta and served as Director of Clinical Research at icddr, b in the 1990s.
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A simple oral rehydration therapy ( ORS ) can be made by dissolving one teaspoon of salt, eight teaspoons of sugar and the juice of an orange into one litre of clean water.
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Thus, the oral rehydration therapy ( ORT ) for replenishing the massive fluid loss in cholera patients, has saved innumerable lives, should be considered as a direct outcome of De's discovery of cholera toxin.
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Oral rehydration therapy ( ORT ) has helped to reduce diarrhea deaths by half, saving an estimated 1 million lives annually; yet more than 2 million children still die from diarrhea-related causes each year.
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In 2006 Dr . Mahalanabis, Dr . Richard A . Cash and Dr . David Nalin were awarded the Prince Mahidol Prize, also for their role in the development and application of oral rehydration therapy.
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International health organizations have been trying to check the disease by improving the quality of drinking water and supplying children with a special mixture of water, sugar and salt, called oral rehydration therapy, that stops diarrhea.
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Working with national governments, UNICEF has sharply reduced the incidence of childhood diseases, from malaria and leprosy in the 1950s to diarrheal illnesses in the 1980s, when the U . N . agency introduced oral rehydration therapy worldwide.
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In 2002 Dr . Mahalanabis, Dr . Nathaniel Pierce, Dr . David Nalin and Dr . Norbert Hirschhorn, were awarded the first Pollin Prize in Pediatric Research for their contributions to the discovery and implementation of oral rehydration therapy.
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