41. Pepsin also undergoes feedback inhibition; a product of protein digestion slows down the reaction by inhibiting pepsin . 42. Each time something acid is consumed or acid is refluxed, pepsins are activated and the symptoms worsen. 43. Its low pH denatures proteins and thereby makes them susceptible to degradation by digestive enzymes such as pepsin . 44. The low pH also activates the enzyme precursor pepsinogen into the active enzyme pepsin by self-cleavage. 45. Using pepsin , they were the first to discern the diffraction pattern of a wet, globular protein. 46. Therefore, pepsin in solution of up to pH 8.0 can be reactivated upon re-acidification. 47. He and his group invented a vaccine for hepatitis B by treating blood serum with pepsin , urea and formaldehyde. 48. Upon cellular uptake, pepsin is stored in intracellular vesicles of low pH at which its enzymatic activity would be restored. 49. A rapid non-invasive pepsin diagnostic called Peptest is now available which determines the presence of pepsin in saliva samples. 50. A rapid non-invasive pepsin diagnostic called Peptest is now available which determines the presence of pepsin in saliva samples.
