The periplasm contains the peptidoglycan layer and many proteins responsible for substrate binding or hydrolysis and reception of extracellular signals.
42.
Beta-lactam antibiotics inhibit the formation of the peptidoglycan layer of the cell walls of Gram-positive bacteria.
43.
Glycoside hydrolase family 73 CAZY GH _ 73 includes peptidoglycan hydrolases with endo-?-N-acetylglucosaminidase specificity.
44.
These enzymes ( PBPs ) are involved in peptidoglycan synthesis which is a major component of the bacterial cell wall.
45.
The large CV I complexes become trapped within the gram-positive cell due to the multilayered nature of its peptidoglycan.
46.
Gram-negative bacteria generally possess a thin layer of peptidoglycan between two membranes ( " diderms " ).
47.
Thus, presence of high levels of peptidoglycan is the primary determinant of the characterisation of bacteria as gram-positive.
48.
For both gram-positive and gram-negative bacteria, particles of approximately 2 nm can pass through the peptidoglycan.
49.
?-lactam antibiotics are bacteriocidal, and act by inhibiting the synthesis of the peptidoglycan layer of bacterial cell walls.
50.
One of the first toxins to be expressed is tracheal cytotoxin, which is a disaccharide-tetrapeptide derived from peptidoglycan.
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