41. This leads to phosphorylase kinase and glycogen phosphorylase 's becoming inactive, while glycogen synthase is activated. 42. In 1956 enzyme liver phosphorylase is inactivated; but when it is activated, it incorporates a phosphate. 43. Phosphorylase a is the enzyme responsible for the release of glucose-1-phosphate from glycogen polymers.44. In mammals, the major isozymes of glycogen phosphorylase are found in muscle, liver, and brain. 45. The brain isoform of glycogen phosphorylase ( PYGB ) has been proposed as a biomarker for gastric cancer. 46. In the end, phosphorylase is kept in its active form and glycogen synthase in its inactive form. 47. Phosphorylase kinase phosphorylates glycogen phosphorylase, which then phosphorylates glycogen and converts it to glucose-6-phosphate.48. Phosphorylase kinase phosphorylates glycogen phosphorylase , which then phosphorylates glycogen and converts it to glucose-6-phosphate. 49. Like in bacteria, polyadenylation by polynucleotide phosphorylase promotes degradation of the RNA in plastids and likely also archaea. 50. When phosphorylase has digested a glycogen branch down to four glucose residues, it will not remove further residues.
