41. Antibodies are secreted by B cells of the adaptive immune system, mostly by differentiated B cells called plasma cells . 42. The result is a proliferation of a plasma cell clone and genomic instability that leads to further mutations and translocations. 43. The plasma cells are said to be monoclonal and the excessively produced antibody is known as monoclonal protein or paraprotein. 44. Pathological studies revealed an encephalitis of the midbrain and basal ganglia, with lymphocyte ( predominantly plasma cell ) infiltration. 45. Just before the season began, Baylor was found to have multiple myeloma, cancur ` gf the blood plasma cells . 46. Antibodies can be secreted into the extracellular environment or anchored in the membranes of specialized B cells known as plasma cells . 47. Polymeric IgA ( mainly the secretory dimer ) is produced by plasma cells in the lamina propria adjacent to mucosal surfaces. 48. ATTR is suspected in people with family history of idiopathic neuropathies or heart failure who lack evidence of plasma cell dyscrasias. 49. "' Inflammatory myofibroblastic tumour "'is a lesional pattern of inflammatory pseudotumour, as plasma cell granuloma. 50. For example, plasma cells will likely secrete IgG3 antibodies if they matured in the presence of the cytokine interferon-gamma.
