41. In patients with endometrial cancer who use progestin releasing IUDs concluded mixed results. 42. The main hormones involved are estrogen, progesterone and a drug called progestin . 43. _Progestin can cause bloating and breast tenderness. 44. Progestin counters that risk, which is why the hormones are given in combination.45. The new study suggests that some of the risk is due to the progestin . 46. So, should women currently taking both estrogen and progestin stop taking the latter? 47. Women would take one progestin pill immediately and a second one 12 hours later. 48. Researchers in Australia also say they have successfully tested a progestin -testosterone combination. 49. This effect is caused by the ability of some progestins to inhibit androgen receptors. 50. It contains 69 percent of progestin found in the original Depo-Provera shot.