41. A prostaglandin known as alprostadil is already on the market to treat male impotence. 42. -- NexMed : alprostadil, a variant of prostaglandin E-1 cream. 43. Waterford said NSAIDs work by inhibiting enzymes that the body uses to manufacture prostaglandins . 44. NSAIDs can combat inflammation by inhibiting prostaglandin synthesis. 45. Different prostaglandins raise or lower blood pressure and regulate muscle activity and glandular secretion. 46. Research has found it inhibits biosynthesis of prostaglandins , which cause pain and inflammation. 47. Acetaminophen also may increase blood pressure by affecting prostaglandin production, the researchers said. 48. The negative effect of hyperinsulinemia on prostaglandin PGE1 / PGE2 balance may be significant. 49. Prostaglandins have two derivatives : prostacyclins and thromboxanes.50. For prostaglandins , this is often indicated by Greek letters ( e . g.