41. Physical examination may reveal pitting peripheral edema, ascites, and hepatojugular reflux . 42. Usually, the entire condensate is initially returned to the column as reflux . 43. These include peptic strictures caused by esophageal reflux and perforations of the esophagus. 44. Children with CdLS often suffer from gastrointestinal tract difficulties, particularly gastroesophageal reflux . 45. Related to this is the question of gastric reflux . 46. The most common gastrointestinal problems include constipation from imperforated anuses and gastroesophageal reflux . 47. The diagram shows a typical reflux apparatus for applying energy to chemical reactions. 48. Originally diagnosed as acid reflux , further tests revealed the problem as achalasia. 49. This may have resulted in less acid reflux and a false negative test. 50. During the reflux thalidomide crystallizes out of the mixture.