While it has been observed in a variety of cell types, it has been best studied in the sarcomere of skeletal myocytes.
42.
It is the tropomyosin binding and thin filament anchoring subunit of the troponin complex in the sarcomeres of slow twitch skeletal muscle fibers.
43.
CMyBP-C is not essential for sarcomere formation during embryogenesis, but is crucial for sarcomere organization and maintenance of normal cardiac function.
44.
CMyBP-C is not essential for sarcomere formation during embryogenesis, but is crucial for sarcomere organization and maintenance of normal cardiac function.
45.
Furthermore, cMyBP-C contributes to the regulation of cardiac contraction at short sarcomere length and is required for complete relaxation in diastole.
46.
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs.
47.
When the muscle no longer needs to contract, the calcium ions are pumped from the sarcomere and back into storage in the sarcoplasmic reticulum.
48.
In striated muscle, such as meat cuts, can show structural coloration or iridescence due to this periodic alignment of the fibrils and sarcomeres.
49.
Muscle tropomyosin isoforms are involved in regulating interactions between actin and myosin in the muscle sarcomere and play a pivotal role in regulated muscle contraction.
50.
The myofibrils are composed of actin and myosin filaments, repeated in units called sarcomeres, which are the basic functional units of the muscle fiber.
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