Spectrin subunits may also be cleaved by caspase family enzymes, and calpain and caspase produce different spectrin breakdown products which can be detected by western blotting with appropriate antibodies.
42.
Spectrin subunits may also be cleaved by caspase family enzymes, and calpain and caspase produce different spectrin breakdown products which can be detected by western blotting with appropriate antibodies.
43.
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
44.
Adducins are membrane-skeletal proteins that cap the growing ends of actin filaments and promote their association with spectrin, another cytoskeletal protein, to create stable and integrated cytoskeletal networks.
45.
In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the blebs and ultimately to be degraded, usually leading to the death of the cell.
46.
HPP has been associated with a defect of the erythrocyte membrane protein spectrin and with spectrin deficiency . It was characterized in 1975 . It is considered a severe form of hereditary elliptocytosis.
47.
HPP has been associated with a defect of the erythrocyte membrane protein spectrin and with spectrin deficiency . It was characterized in 1975 . It is considered a severe form of hereditary elliptocytosis.
48.
This is caused by a molecular defect in one or more of the proteins of the red blood cell cytoskeleton, including spectrin, ankyrin, Band 3, or Protein 4.2.
49.
In 2013, PRC1 was illustrated as a lengthy molecule consisting of a C-terminal spectrin microtubule-binding domain, an extended rod domain, and an N-terminal dimerization domain.
50.
This variant of haploinsufficiency is only seen in two other human diseases : Erythropoietic protoporphyria, caused by mutations in the FECH gene; and hereditary elliptocytosis, caused by mutations in the spectrin gene.
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