As analogs of thymidine, this type of drugs are readily phosphorylated to 5'- monophosphates.
42.
AZT is used as substrate in one of the methods for determination of thymidine kinase in serum.
43.
The amounts of thymidine kinase found by this method does not correlate well with the enzyme activities.
44.
Thymidine phosphorylase has also been found to play a dual role in both cancer development and therapy.
45.
Tipiracil helps maintain the blood concentration of trifluridine by inhibiting the enzyme thymidine phosphorylase which metabolizes trifluridine.
46.
There are several reports of the utility of thymidine kinase activity measurements in serum in lung cancer.
47.
Thymidylate kinase can phosphorylate TMP into thymidine diphosphate, which nucleoside diphosphate kinase can phosphorylate into thymidine triphosphate.
48.
Thymidylate kinase can phosphorylate TMP into thymidine diphosphate, which nucleoside diphosphate kinase can phosphorylate into thymidine triphosphate.
49.
The highest number of patients identified was obtained by combination of thymidine kinase and Ki-67 staining.
50.
This is because thymidine is found in deoxyribonucleic acid ( DNA ) and not ribonucleic acid ( RNA ).
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