Dr . Ramsey's work also revealed how trophoblastic cells spread along the inner wall of the placental arteries, in a frequently cited image, " like wax dripping down a candle ."
42.
"' StAR-related lipid transfer domain protein 7 "'( STARD7 ) or gestational trophoblastic tumor gene-1 ( GTT1 ) is a lipid transporter that specifically binds and transports phosphatidylcholine between membranes.
43.
Postoperatively, patients with conservative surgical therapy are at risk for development of a persistent ectopic pregnancy due to the presence of deeply embedded surviving trophoblastic tissue; thus, monitoring of hCG levels is indicated until they become undetectable.
44.
The work of Patrizia Paterlini-Br�chot led to the discovery of the ISET technique ( ISET Test Isolation by Size of Epithelial Tumor / Trophoblastic Cells ) permitting the isolation and characterization of both circulating tumor and fetal cells.
45.
Barry Hancock, director of a clinic at Weston Park Hospital in Sheffield that specializes in the treatment of trophoblastic cancers, agrees that abnormal imprinting in the genes of cloned human embryos may increase a mother's risk of the disease.
46.
Gestational trophoblastic disease like hydatidiform moles ( " molar pregnancy " ) or choriocarcinoma may produce high levels of ?hCG ( due to the presence of syncytialtrophoblasts-part of the villi that make up the placenta ) despite the absence of an embryo.
47.
Persistent disease; persistent GTD : If there is any evidence of persistence of GTD, usually defined as persistent elevation of beta hCG ( see �Diagnosis?below ), the condition may also be referred to as gestational trophoblastic neoplasia ( GTN ).
48.
A common process is especially suggested by observations in animals with an epitheliochorial placenta like pigs and camels : here, the epithelium is not breached and the mature placenta consists of extensive interdigitation of very long trophoblastic and uterine epithelial microvilli throughout pregnancy.
49.
Several years later at the National Cancer Institute, Roy Hertz and Min Chiu Li then demonstrated complete remission in women with choriocarcinoma and chorioadenoma in 1956, discovering that methotrexate alone could cure choriocarcinoma ( 1958 ), a germ-cell malignancy that originates in trophoblastic cells of the placenta.
50.
Histologically the diagnosis has been made by Rubin s criteria on the surgical specimen : cervical glands are opposite the trophoblastic tissue, the trophoblastic attachment is below the entrance of the uterine vessels to the uterus or the anterior peritoneal reflection, and fetal elements are absent from the uterine corpus.
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