1. At the molecular level amanitin toxins cause damage to cells of these organs. 2. The oral of ?-amanitin is approximately 0.1 mg / kg. 3. ?-Amanitin can also be used to determine which types of RNA polymerase are present. 4. This is done by testing the sensitivity of the polymerase in the presence of ?-amanitin . 5. ?-amanitin is able to travel through the bloodstream to reach the organs in the body. 6. An example of a toxic peptide is alpha-amanitin , which is found in relatives of the death cap mushroom. 7. Its principal toxic constituent, ?-amanitin , damages the liver and kidneys, often fatally, and has no known antidote. 8. The genes encoding the proprotein for ?-amanitin belongs to the same family as those that encode for phallacidin ( a phallotoxin ). 9. The tolerability and therapeutic window of amanitin -based ADCs has been determined in a variety of rodent and non-human primate models. 10. In this case, the amanitin is diluted by " D4 " ( 1 : 10000 ) and 5-40 drops are given.
