1. This results in a type of surfactant that usually is classified as amphipathic . 2. It is predicted to function through protein-protein interactions via two amphipathic helices. 3. Lipids are a broad category of mid-sized molecules that are hydrophobic or amphipathic . 4. The " easy " way to do this is with water and an amphipathic lipid. 5. The structure consists of two central primarily hydrophobic ?-helices surrounded by amphipathic helices. 6. This interaction occurs along a so-called binding groove or cleft that is amphipathic in nature. 7. Due to the 4 positive arginines along with nine hydrophobic amino acids, Arenicin-3 is amphipathic . 8. Additionally, it catalyzes flipping of several anionic amphipathic molecules such as phospholipid bilayer to the other monolayer. 9. The amphipathic helix residues ( 46 62 ) within the cytoplasmic tail play role in virus budding and assembly. 10. A second loop precedes large " amphipathic ?-helix " ( hA ) that longitudinally spans protein site.