1. Progression from metaphase to anaphase is marked by sister chromatid separation. 2. This is because in anaphase I the homologous chromosomes are separated. 3. Micronuclei formation may also result from chromosome malsegregation during anaphase . 4. Overall, securin and separase act in an anaphase -regulating network. 5. After the error is corrected, the cell will proceed to anaphase . 6. These stages are prophase, prometaphase, metaphase, anaphase , and telophase. 7. Scheme showing cell cycle progression between prometaphase and anaphase . 8. Upon anaphase onset and removal of inhibitory CDK1 phosphorylation, PRC1 dimers form. 9. The Metaphase Anaphase transitions all act as biochemical switches in the cell cycle. 10. In " nondisjunction ", sister chromatids fail to separate during anaphase .
