1. It consists of a descending limb and an ascending limb . 2. This makes the thick ascending limb impermeable to water. 3. The medullary ascending limb remains impermeable to water. 4. Considerable differences aid in distinguishing the descending and ascending limbs of the loop of Henle. 5. Vasopressin stimulates sodium chloride reabsorption in the thick ascending limb of the nephron by activating signaling pathways. 6. The point where DCT contacts the cortical thick ascending limb of the loop of Henle is called macula densa. 7. The thick ascending limb of the loop of Henle begins at the deeper portion of the renal outer medulla. 8. This outward movement of sodium and the lack of water permeability in the thick ascending limb , creates a more diluted urine. 9. "' Bartter syndrome "'is a rare inherited defect in the thick ascending limb of the loop of Henle. 10. The ascending limb of the loop of Henle receives an even lower volume of fluid and has different characteristics compared to the descending limb.
