1. Ursodiol is the only FDA approved drug to treat primary biliary cirrhosis . 2. The TNPO3-IRF5 locus is implicated in primary biliary cirrhosis and systemic sclerosis. 3. Overlapping presentation with primary biliary cirrhosis and primary sclerosing cholangitis has been observed. 4. "' Anti-sp100 antibodies "'are found in association with primary biliary cirrhosis . 5. Primary biliary cirrhosis is an autoimmune disease of the liver. 6. It is characterized by inflammation, fibrosis, destruction of the biliary tree and biliary cirrhosis . 7. Initial transient neonatal jaundice advances over time to biliary cirrhosis with severe liver fibrosis. 8. With Charcot, he performed important research of obstructive biliary cirrhosis . 9. Modafinil has been shown to improve excessive daytime somnolence and fatigue in primary biliary cirrhosis . 10. Tendon xanthomas are associated with type II hyperlipidemia, chronic biliary tract obstruction, and primary biliary cirrhosis .
