1. Cardiotoxicity is a major problem with people treated with higher dose regimens.2. Like Doxil, the liposomal encapsulation of the doxorubicin limits the cardiotoxicity . 3. Adverse CNS effects may indicate impending cardiotoxicity and should be carefully monitored. 4. Their main adverse effect is cardiotoxicity , which considerably limits their usefulness. 5. Effort soon began to develop derivatives with better activity and less cardiotoxicity . 6. Significant research has gone into finding ways to attenuate Doxorubicin-mediated cardiotoxicity . 7. It is used only topically due to cardiotoxicity . 8. It can be associated with cardiotoxicity . 9. The study found that cardiotoxicity might have been widespread in animal life exposed to the spill. 10. It produces less cardiotoxicity than anthracycline-based treatments and hence may be preferable in these patients.
