1. These proteins organize the DNA into a compact structure called chromatin . 2. Since then, over several decades, chromatin theory has evolved. 3. Hyperacetylated chromatin is transcriptionally active, and hypoacetylated chromatin is silent. 4. Hyperacetylated chromatin is transcriptionally active, and hypoacetylated chromatin is silent. 5. AR acetylation is induced by androgens and determines recruitment into chromatin . 6. O-glycosylation of H1 may promote chromatin condensation and compaction. 7. This disrupts chromatin and opens up the transcription-binding domains. 8. RCC1 is bound to chromatin and therefore located inside the nucleus. 9. It is also present in protein complexes involved in chromatin assembly. 10. The process is guided by small RNAs and epigenetic chromatin marks.
