1. Most cases of coloboma affect only the iris. 2. Other conditions can be associated with a coloboma . 3. A coloboma can occur in one eye ( unilateral ) or both eyes ( bilateral ). 4. People with coloboma may have no vision problems or may be blind, depending on severity. 5. Sensorineural hearing loss can be another measure for proper diagnosis as well as checking for ocular coloboma . 6. Like most other eye conditions, a diagnosis of optic nerve coloboma precludes a person from certain occupations. 7. The informant said that the girl she had seen had the same coloboma of the iris as Madeleine. 8. Dysgenesis of the vesicle later in development may result in coloboma , a separate and less severe malformation of the ocular structures. 9. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia, and coloboma . 10. Other conditions of note include iris coloboma , canine hip dysplasia, Pelger-Huet anomaly, hypothyroidism, and nasal solar dermatitis.
