1. Atrial natriuretic peptide causes the distal convoluted tubule to secrete more sodium. 2. This hypotonic filtrate is passed to the distal convoluted tubule in the renal cortex. 3. The distal convoluted tubule has a different structure and function to that of the proximal convoluted tubule. 4. Much of the ion transport taking place in the distal convoluted tubule is regulated by the endocrine system. 5. In the presence of parathyroid hormone, the distal convoluted tubule reabsorbs more calcium and secretes more phosphate. 6. Use of carbenicillin can cause hypokalemia by promoting potassium loss at the distal convoluted tubule of the kidney. 7. Inorganic fluoride inhibits adenylate cyclase activity required for antidiuretic hormone effect on the distal convoluted tubule of the kidney. 8. This cell membrane protein participates in the control of ion homeostasis at the distal convoluted tubule portion of the nephron. 9. GST-Pi is expressed in many human tissues, particularly in the biliary tree and renal distal convoluted tubules . 10. Chlortalidone prevents reabsorption of sodium and chloride by inhibiting the Na + / Cl " symporter in the distal convoluted tubule .
