1. It was implicated in the outbreak of encephalitis lethargica in the 1920s. 2. Encephalitis lethargica is identified by high fever, headache, delayed physical response, and lethargy.3. Historically encephalitis lethargica was referred to as " Cruchet's disease ". 4. It bears similarity to conditions such as encephalitis lethargica and neuroleptic malignant syndrome. 5. From 1917 to 1928, an epidemic of encephalitis lethargica occurred worldwide. 6. Specifically, he questions Whitaker's assertion that Kraepelin's schizophrenia patients in fact suffered from encephalitis lethargica . 7. Treatment for encephalitis lethargica in the early stages is patient stabilization, which may be very difficult. 8. During the run Muriel Hewitt began to show early symptoms of encephalitis lethargica , a progressive and ultimately fatal illness. 9. Individuals can exhibit upper body weakness, muscular pains, and tremors, though the cause of encephalitis lethargica is not currently known. 10. In the winter of 1915-16 he was the first physician to give a report on encephalitis lethargica ( Economo's disease ).