1. Anti-K does not bind complement, therefore hemolysis is extravascular . 2. Clevidipine is rapidly metabolized by esterases in the blood and extravascular tissues. 3. Affects medium and small vessels with vascular and extravascular granulomatosis. 4. Therefore, haptoglobin is not a reliable way to differentiate between intravascular and extravascular hemolysis. 5. The model ignores intracellular and extravascular compartments. 6. As a result, approximately 12 % of blood plasma volume will cross into the extravascular compartment. 7. The Schumm test is used to differentiate intravascular haemolysis from extravascular haemolysis, as in haemolytic anaemias. 8. Extravascular or autochthonous bubbles usually form in slow tissues such as joints, tendons and muscle sheaths.9. In hereditary spherocytosis, red blood cells fail to pass through and get phagocytosed, causing extravascular hemolysis. 10. This is caused by the accumulation of extracellular and extravascular fluid within confined anatomic spaces of the extremities or digits.
