1. One possible explanation involves a class of steroid hormones called glucocorticoids . 2. Glucocorticoids can damage neurons in the hippocampi of rodents and primates.3. Therapies include immunosuppressive drugs and, in some cases, glucocorticoids . 4. Cortisol ( or hydrocortisone ) is the most important human glucocorticoid . 5. This results in a molecule with no glucocorticoid or mineralocorticoid activity. 6. Permissive actions of glucocorticoids like cortisol generally occur at low concentrations. 7. The glucocorticoid gene is activated, resulting in lowered stress response. 8. 9 . Being treated with glucocorticoids or other drugs affecting bone metabolism. 9. GCs affect cells by binding to the glucocorticoid receptor ( GR ). 10. An enzyme exists in mineralocorticoid target tissues to prevent overstimulation by glucocorticoids .