1. Medullary sinuses contain histiocytes ( immobile macrophages ) and reticular cells. 2. In CT, they give rise to macrophages ( histiocytes ). 3. The cells may be phagocytosed by histiocytes or multinucleated giant cells. 4. Macrophages ( specifically histiocytes ) are the cells that define a granuloma. 5. It replicates intracellularly inside histiocytes and nerve cells and has two forms. 6. It is a collection of immune cells known as histiocytes . 7. Some sources consider Langerhans cell derivatives to be histiocytes . 8. The most common histiocyte disorders are Langerhans'cell histiocytosis and haemophagocytic lymphohistiocytosis. 9. Histologically, these are collections of chronic inflammatory cells, mainly lymphocytes and histiocytes . 10. Notice the irregular nuclear contours of the medium-sized lymphoma cells and the presence of a pink histiocyte .