1. The biochemical mechanisms by which hormesis works are not well understood. 2. The idea of radiation hormesis is considered unproven by regulatory bodies. 3. Hormetics is the term proposed for the study and science of hormesis . 4. Hormesis may also be induced by endogenously produced, potentially toxic agents.5. In 2001 a one-page addendum on radiation hormesis was added. 6. The hormesis model of dose response is vigorously debated. 7. The hypothesis of hormesis has generated the most controversy when applied to ionizing radiation. 8. The eponymous " Hueppe s rule " is an historical term synonymous with hormesis . 9. Hormesis remains largely unknown to the public.10. Oxidative stress ( as formulated in mitohormesis or mitochondrial hormesis on a purely hypothetical basis.
