1. The enzyme most responsible for estradiol 4-hydroxylation is CYP1B1. 2. This enzyme participates in tyrosine metabolism and benzoate degradation via hydroxylation . 3. This enzyme participates in benzoate degradation via hydroxylation and carbazole degradation. 4. Tyrosine is created from phenylalanine by hydroxylation by the enzyme phenylalanine hydroxylase. 5. The remainder is extensively metabolized by hydroxylation , hydrolysis, and glucuronidation. 6. Each of which is necessary for effective substrate hydroxylation and NADH oxidation. 7. ?-Hydroxylation with oxaziridines has been widely implemented in total synthesis. 8. :For the latter part, see rancidification and I think Hydroxylation . 9. Amination and hydroxylation has been observed for substituted pyrimidines. 10. "' Hydroxylation of phenylalanine by ferryl oxo intermediate . "'
