1. Copper 8-hydroxyquinoline is sometimes included in paint to prevent mildew. 2. The compound is an 8-hydroxyquinoline , a common chelating agent. 3. There are also many non-antibacterial medical uses for 4-hydroxyquinoline . 4. Aniline reacts with another equivalent of benzoylacetanilide before forming the 4-hydroxyquinoline . 5. Continuation of this reaction using the Conrad-Limpach mechanism led to the synthesis of 2-hydroxyquinoline . 6. A 1964 study found that with certain reaction conditions formation of a 4-hydroxyquinoline is a competing reaction. 7. Furthermore, the type of solvent used is very important to ensuring high yields of the 4-hydroxyquinoline product. 8. The initial synthesis of 2-hydroxyquinoline from a ?-ketoanilide was reported in 1886 as the Knorr quinoline synthesis. 9. Thus, 8-hydroxyquinoline is potentially useful to control American plants that have become invasive weeds in the diffuse knapweed's native range. 10. SDB-005 is the indazole core analogue of PB-22 where the 8-hydroxyquinoline has also been replaced with a naphthalene group.