1. In these cases, ACTH levels remain low and no hyperpigmentation develops. 2. Affected dogs can suffer from red hyperpigmentation , lichenification, and hair loss. 3. Improvement in skin hyperpigmentation is typically seen within six months when used twice daily. 4. Hydroquinone is ineffective for hyperpigmentation affecting deeper layers of skin such as the dermis. 5. Hyperpigmentation of the skin occurs in almost half; some also have skin nodules.6. The most common is non-specific hyperpigmentation . 7. LET resolves with normal skin, no residual scarring, no hyperpigmentation or hypopigmentation. 8. It demonstrates hyperpigmentation of the colon with white lymph nodes showing through on colonoscopy. 9. If they do not receive treatment, the affected sites may develop permanent hyperpigmentation or hypopigmentation. 10. "Hyperchromia " can refer to hyperpigmentation , and " hypochromia " can refer to hypopigmentation.
