1. Some species contain only one spliced leader sequence found on all mRNAs. 2. This leader sequence is very important for the regulation of histidine in " E . coli ". 3. In this system the full leader sequence has 4 blocks of complementary strands that can form hairpin loops structures. 4. The leader sequence can assume two different secondary structures known as the terminator and the anti-terminator structure. 5. This leader sequence can assume two different secondary structures known as the terminator and the anti-terminator structure. 6. The CRISPR array comprises an AT-rich leader sequence followed by short repeats that are separated by unique spacers. 7. In each a leader sequence of 150-200 bp is found upstream of the first gene in the operon. 8. Monomeric retinoschisin contains 224 amino acids with a leader sequence that is cleaved off upon preparation in the cell for secretion. 9. New spacers are added to a CRISPR array in a directional manner, but not exclusively, adjacent to the leader sequence . 10. "' RncO "'is a bacterial non-coding RNA regulatory element found in the rnc leader sequence .