1. The cysteinyl leukotrienes , potent biological compounds derived from arachidonic acid. 2. Leukotrienes also have a powerful effect in bronchoconstriction and increase vascular permeability.3. The three types of eicosanoids are prostaglandins, thromboxanes, and leukotrienes . 4. Examples of animal hormones subjected to ion trapping include Prostacyclin and Leukotrienes . 5. Zyflo and Accolate both focus on leukotrienes , molecules that trigger asthma attacks. 6. Leukotrienes are very important agents in the inflammatory response.7. Discovery of leukotrienes led to the Nobel Prize in 1982 for Swedish scientist Bengt Samuelsson. 8. These drugs block leukotrienes , substances that, like histamines, are released during inflammation. 9. They also secrete lipid mediators like leukotrienes ( LTD-4 ), and several cytokines. 10. Leukotriene antagonists are used to treat these disorders by inhibiting the production or activity of leukotrienes .
