11. For a description of melanin-related disorders, see melanin, melanosis coli and ocular melanosis . 12. Such lesions indicate pneumonia, emphysema, hydatidosis, anthracosis, pleurisy, melanosis , and tuberculosis. 13. Chemotherapy and radiotherapy have been shown to be ineffective in cases of neurocutaneous melanosis where malignancy is present. 14. The morbid deposition of black matter, often of a malignant character causing pigmented tumors, is called melanosis . 15. In Caucasians these granules are not expected to influence on the clinically observed degree of smoker's melanosis . 16. This wide range is most likely due to the large number of asymptomatic, undiagnosed patients with neurocutaneous melanosis . 17. In one study, 4-hexylresorcinol increased the shelf life of shrimp by reducing melanosis ( black spots ). 18. Approximately 10 % of patient with neurocutaneous melanosis also present the Dandy Walker syndrome and associated Dandy-Walker malformation. 19. Neurocutaneous melanosis is associated with the presence of either giant congenital melanocytic nevi or non-giant nevi of the skin. 20. It is estimated that neurocutaneous melanosis is present in 2 % to 45 % of patients with giant congenital melanocytic nevi.